Preparation of 4-haloazetidin-2-ones from 4-sulfinoazetidin-2-on

Details Preparation of 4-haloazetidin-2-ones from 4-sulfinoazetidin-2-on Preparation of 4-haloazetidin-2-ones from 4-sulfinoazetidin-2-on

1981-03-09

1983-01-11

Berch, Mark L.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

2602393R, 2602454, 2603303, 546208, 2603309, C07D20508, C07B 900, C07D40304, C07D40104

Patent

active

043681565

ABSTRACT:
Process for 4-halo azetidinones of the formula ##STR1## wherein R.sub.1 is acylamino or diacylamino, X is chloro, bromo or iodo, and R is a carboxy-protecting group which comprises treating a 4-sulfinoazetidinone of the formula ##STR2## with positive halogen reagent, eg. N-chlorosuccinimide, N-bromosuccinimide, N-iodosuccinimide, hypohalite. The 4-haloazetidinones are useful intermediate for .beta.-lactam antibiotics.

REFERENCES:
patent: 4013653 (1977-03-01), Wolfe
patent: 4081440 (1979-03-01), Kukolja
patent: 4138486 (1979-02-01), Narisada et al.
patent: 4159266 (1979-06-01), Kukolja
Campbell, J.C.S. Perkins I, p. 1208, (1975).

Affiliated with

Also associated with

Rating

Preparation of 4-haloazetidin-2-ones from 4-sulfinoazetidin-2-on does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Preparation of 4-haloazetidin-2-ones from 4-sulfinoazetidin-2-on, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Preparation of 4-haloazetidin-2-ones from 4-sulfinoazetidin-2-on will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-778116