Preparation of 4-acetals of butene-1,4-dial and novel acetals of

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

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560174, 562577, 564502, 568461, C07D31906, C07C 6966, C07C 59147, C07C 4500

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active

051625520

ABSTRACT:
A process for the preparation of 4-acetals of butene-1,4-dial of the formula ##STR1## where R is an alkyl, alkenyl, cycloalkyl or aralkyl radical of 1 to 12 carbon atoms which may contain alkoxy groups, or the two radicals R together form an alkylene or alkenylene radical of 2 to 10 carbon atoms which may contain alkoxy groups, and R.sup.1 is an alkyl, alkenyl or alkynyl radical of 1 to 12 carbon atoms which may be substituted by cycloaliphatic, aromatic or heterocyclic radicals or by hydroxyl, ether, thioether, acyl, alkylamino, carboxyl or carbalkoxy groups, or is an unsubstituted or substituted aryl radical or an alkoxy, alkylthio or acyloxy group, wherein a glyoxal monoacetal of the formula ##STR2## is reacted with an aldehyde of the formula

REFERENCES:
March, Advanced Organic Chemistry: Reactions, Medianisms, and Structure, p. 671 (1968).
March, Advanced Organic Chemistry: Reactions, Mechanisms and Structure p. 670 (1968).
Beilsteins Handbuch der Organischen Chemie, 1922, vol. 4, p. 54.
Chemische Berichte 93, pp. 1305-1306 (1960).
Angewandte Chemie 88, p. 261 (1976).
J. Heterocyclic Chem. 7, pp. 1153-1155 (1970).
J. Chem. Soc. (C), 1971, pp. 2984-2985.
March, Advanced Organic Chemistry, 1968, pp. 670-671, 692-693.

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