Organic compounds -- part of the class 532-570 series – Organic compounds – Nitrogen attached directly or indirectly to the purine ring...
Patent
1976-10-18
1978-05-30
Coughlan, Jr., Paul M.
Organic compounds -- part of the class 532-570 series
Organic compounds
Nitrogen attached directly or indirectly to the purine ring...
260154, C07D47334
Patent
active
040923142
ABSTRACT:
The present invention relates to a novel and useful process for preparing 4,6-diamino-5-arylazopyrimidine from an arylazomalononitrile in the presence of ammonium chloride and formamide. If desired, the 4,6-diamino-5-arylazopyrimidine may then be hydrogenated to form 4,5,6-triaminopyrimidine which, when the hydrogenation is carried out in the presence of formic acid or its derivative, gives adenine.
Reinhold Donald F.
Vander Zwan Michael C.
Coughlan, Jr. Paul M.
Merck & Co. , Inc.
Patton Walter
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