Preparation of 3-oxo-.DELTA..sup.1,4 -steroids

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing compound containing a...

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435 55, C12P 3302, C12P 3316

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048392820

ABSTRACT:
A process for preparing a 3-oxo-.DELTA..sup.1,4 -steroid comprises fermenting the corresponding 3-oxo-.DELTA..sup.4 -steroid, saturated in the 1,2-position, witih a living culture of Arthrobacter simplex in the presence of 0.04 g to 0.12 g of cobalt(II) ions per liter of culture broth.

REFERENCES:
patent: 3388042 (1968-06-01), Arima et al.
patent: 4101378 (1978-07-01), Nishikawa et al.
patent: 4431732 (1984-02-01), Weber et al.

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