Preparation of 3,5-dialkyl-4-hydroxybenzoic acid

Details Preparation of 3,5-dialkyl-4-hydroxybenzoic acid Preparation of 3,5-dialkyl-4-hydroxybenzoic acid

1976-11-03

1978-02-07

Killos, Paul J.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

260520A, C07C 6502

Patent

active

040727076

ABSTRACT:
A process for preparing a sterically hindered 3,5-dialkyl-4-hydroxybenzoic acid which comprises reacting a sterically hindered 2,6-dialkylphenol with an excess of sodium hydride or lithium hydride in a dry dipolar aprotic solvent, carboxylating the resulting anhydrous phenolate with an excess of carbon dioxide at atmospheric pressure and at a temperature of about 70.degree. C. to 80.degree. C., then destroying the excess sodium hydride or lithium hydride by addition of an alcohol, followed by acidifying the reaction mixture to obtain a high yield of the sterically hindered 3,5-dialkyl-4-hydroxybenzoic acid.

REFERENCES:
patent: 2749362 (1956-06-01), Berni
patent: 3187037 (1965-06-01), Giesen et al.
patent: 3435068 (1969-03-01), Gehring et al.
patent: 3532745 (1970-10-01), Hirao
patent: 3825593 (1974-07-01), Meek
patent: 3870744 (1975-03-01), Wagner

Affiliated with

Also associated with

Rating

Preparation of 3,5-dialkyl-4-hydroxybenzoic acid does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Preparation of 3,5-dialkyl-4-hydroxybenzoic acid, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Preparation of 3,5-dialkyl-4-hydroxybenzoic acid will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1400786