Preparation of 2-t-butyl-5-chloropyrimidine

Details Preparation of 2-t-butyl-5-chloropyrimidine Preparation of 2-t-butyl-5-chloropyrimidine

1982-08-02

1984-12-04

Hollrah, Glennon H.

Organic compounds -- part of the class 532-570 series

Organic compounds

Nitrogen attached directly or indirectly to the purine ring...

544243, 544321, 544323, C07D23930

Patent

active

044865902

ABSTRACT:
2-t-Butyl-5-chloropyrimidine is made by the direct chlorination of 2-t-butylpyrimidine with elemental chlorine in an acetic or propionic acid solution at temperatures of 40.degree. to 90.degree. C. in the presence of a buffer.

REFERENCES:
patent: 2812328 (1957-11-01), Hepworth
patent: 4299961 (1981-11-01), Pasquale et al.
Blank, "Chemical Abstracts", vol. 89, 1978, col. 90167z.

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