Preparation of 2-alkylpyrimidines

Details Preparation of 2-alkylpyrimidines Preparation of 2-alkylpyrimidines

1981-09-14

1983-03-08

Daus, Donald G.

Organic compounds -- part of the class 532-570 series

Organic compounds

Four or more ring nitrogens in the bicyclo ring system

C07D23926

Patent

active

043762018

ABSTRACT:
A 3-aminopropyl carboxylic acid amide is dehydrogenated and cyclized over a supported platinum or palladium catalyst to prepare 2-alkylpyrimidines in a single step vapor phase reaction.

REFERENCES:
patent: 3050523 (1962-08-01), Erner et al.
patent: 3366634 (1968-01-01), McBride, Jr. et al.
"The Pyrimidines", Interscience Publishers (1962), pp. 455, 445-448.
Okada, et al., Chemical Abstracts, vol. 85, 142251m (1976).
Tsuchiya, et al., Chemical Abstracts, vol. 86, 29475h (1977).
Disteldorf, et al., Chemical Abstracts, vol. 89, 180044m (1978).
Lythgoe, et al., J. Chem. Soc., 1951, pp. 2323-2329 (1951).

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