Preparation of 2-alkyl-4,5-dihydroxymethylimidazoles

Details Preparation of 2-alkyl-4,5-dihydroxymethylimidazoles Preparation of 2-alkyl-4,5-dihydroxymethylimidazoles

1985-07-12

1987-04-14

Schwartz, Richard A.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C07D23364

Patent

active

046580352

ABSTRACT:
2-Alkyl-4,5-dihydroxymethyl-imidazoles of the formula ##STR1## where R is alkyl, are prepared by a process in which an imidazole of the formula ##STR2## is reacted with not less than 2 moles of formaldehyde in the presence of a base.

REFERENCES:
patent: 4104473 (1978-08-01), Sawa et al.
patent: 4189591 (1980-02-01), Mueller et al.
patent: 4278801 (1981-07-01), Kempe et al.
E. F. Godefroi, et al., 91 (1972), Recueil, pp. 1383-1392.
M. Masui, et al., Chem. Pharm. Bulletin, 22 (10), pp. 2359-2364.

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