Preparation of 2,6-disubstituted-5-cyano-4-pyrimidinyloxyacetic

Details Preparation of 2,6-disubstituted-5-cyano-4-pyrimidinyloxyacetic Preparation of 2,6-disubstituted-5-cyano-4-pyrimidinyloxyacetic

1988-07-20

1990-03-06

Lee, Mary C.

Organic compounds -- part of the class 532-570 series

Organic compounds

Nitrogen attached directly or indirectly to the purine ring...

C07D23902

Patent

active

049067532

ABSTRACT:
Disclosed herein are 2,6-disubstituted-5-cyano-4-pyrimidinyloxyacetic acids and pharmaceutically acceptable salts thereof and methods of their preparation. The compounds are new aldose reductase inhibitors useful for the treatment of prevention of diabetic complications.

REFERENCES:
patent: 4505910 (1985-03-01), Bagli
patent: 4568693 (1986-02-01), Sestanj
patent: 4617393 (1986-10-01), Bagli

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