Preparation of 2,4,5-trifluorobenzoic acid by decarboxylation of

Organic compounds -- part of the class 532-570 series – Organic compounds – Carboxylic acids and salts thereof

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562494, C07C 51377, C07C 6310

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active

052330850

ABSTRACT:
3,4,6-Trifluorophthalic acid may be decarboxylated in a controlled manner to form 2,4,5-trifluorobenzoic acid by heating the phthalic acid in a dipolar aprotic solvent in the absence of any catalyst.

REFERENCES:
patent: 4782180 (1988-11-01), Wemple et al.
Yakobson et al., "Zh. Obsch. Khim 36" (1966) pp. 139-142 (in J. Gen. Chem. USSR, translated from Russian, 36 (1966) pp. 144-146.

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