Preparation of 2,4,5-trifluorobenzoic acid by decarboxylation of

Organic compounds -- part of the class 532-570 series – Organic compounds – Carboxylic acids and salts thereof

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C07C 5138

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049355414

ABSTRACT:
It has been discovered that 3,4,6-trifluorophthalic anhydride may be decarboxylated by heating in a polar aprotic solvent to yield 2,4,5-trifluorobenzoic acid.

REFERENCES:
patent: 4769492 (1988-09-01), Kaieda et al.
patent: 4782180 (1988-11-01), Wemple
Bridges, A. et al., J. Org. Chem., 55(2), 773-775, 1990.

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