Preparation of 2,3-dichloro-5-acetylpyridine

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

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C07D21170, C07D21182

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active

051498227

ABSTRACT:
A process for the preparation of 2,3-dichloro-5-acetylpyridine of the formula ##STR1## comprising decarboxylating a compound of the formula ##STR2## in which R.sup.1 stands for methyl or ethyl,
in a mixture of water and a water miscible aprotic solvent.

REFERENCES:
patent: 3591642 (1971-07-01), Szinai et al.
patent: 4358455 (1982-11-01), Atkinson et al.
Fieser et al. Reagents for Org. Synthesis vol. I p. 522, 523, 688 (1967).
American Chemical Journal, vol. XIV. 1892, pp. 480-545.

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