Preparation of 1,3-di(alkoxycarbonylamino)propanes

Organic compounds -- part of the class 532-570 series – Organic compounds – Carboxylic acid esters

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560115, 560158, C07C12507, C07C125073, C07C125075

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046721371

ABSTRACT:
1,3-Di(alkoxycarbonylamino)propanes of the general formula I ##STR1## where R.sup.1, R.sup.2 and R.sup.3 can be identical or different and each is hydrogen, or an aliphatic, cycloaliphatic, araliphatic or aromatic radical, and R.sup.4 is an aliphatic, cycloaliphatic or araliphatic radical, are prepared by reacting an .alpha.,.beta.-unsaturated aldehyde with a carbamic acid ester by reacting in a first stage as the .alpha.,.beta.-unsaturated aldehyde a compound of the general formula II ##STR2## where R.sup.1, R.sup.2 and R.sup.3 have the abovementioned meanings, with a carbamic acid ester of the general formula III ##STR3## where R.sup.4 has the abovementioned meanings, at 0.degree.-150.degree. C. to give a 1,1,3-tri(alkoxycarbonylamino)propane of the general formua IV ##STR4## where R.sup.1, R.sup.2, R.sup.3 and R.sup.4 have the abovementioned meanings, and in a second stage heating the compound of the general formula (IV) in the presence of a hydrogenation catalyst and hydrogen under 1-300 bar at 100.degree.-300.degree. C.

REFERENCES:
patent: 3277098 (1966-10-01), Mexten
Chem. Rev. 65 583 (1965).
Houben-Weyl, 4th ed., vol. VIII, p. 138.

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