Preparation method of biodegradable porous polymer scaffolds...

Coating processes – Medical or dental purpose product; parts; subcombinations;...

Reexamination Certificate

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C427S002240, C427S002310, C427S491000, C427S533000, C427S569000, C427S296000

Reexamination Certificate

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06861087

ABSTRACT:
A method for modifying surface of biodegradable porous polymer scaffold for tissue engineering using a low temperature plasma discharge apparatus, and particularly, a method for inducing the biodegradable porous polymer scaffold to be hydrophilic by graft polymerizing a hydrophilic monomer on the surface of the biodegradable porous polymer scaffold, which is made of polylactic acid, polyglycolic acid or poly(lactic acid-glycolic acid) copolymer, using a low temperature plasma. The surface-modified porous polymer scaffold according to the present invention has an enhanced cell compatibility in cell culture in vitro, and promote tissue growth when the cell is transplanted into a body.

REFERENCES:
patent: 6623749 (2003-09-01), Williams et al.
patent: 20030165613 (2003-09-01), Chappa et al.
patent: 20030198968 (2003-10-01), Matson

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