Preparation method for quetiapine

Details Preparation method for quetiapine Preparation method for quetiapine

2004-09-23

2010-12-28

Coleman, Brenda L (Department: 1624)

Organic compounds -- part of the class 532-570 series

Organic compounds

Unsubstituted hydrocarbyl chain between the ring and the -c-...

Reexamination Certificate

active

07858777

ABSTRACT:
The present invention discloses a process for the preparation of quetiapine, which comprises the ring closure and deprotection of a compound of the formula (I), as well as novel intermediates in the process.

REFERENCES:
patent: 3539573 (1970-11-01), Schmutz et al.
patent: 2007/0111987 (2007-05-01), Rummakko et al.
patent: 0 240 228 (1987-10-01), None
patent: 0 282 236 (1988-09-01), None
patent: WO-01/55125 (2001-08-01), None
Warawa et al., Journal of Medicinal Chemistry, American Chemical Society, Washington, US, vol. 44, Feb. 1, 2001, pp. 372-389.

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