Preparation for skin and mucous membrane

Details Preparation for skin and mucous membrane Preparation for skin and mucous membrane

1994-06-23

1996-11-12

Ivy, C. Warren

Drug, bio-affecting and body treating compositions

Inorganic active ingredient containing

Nitrates or nitrites or nitric acid or nitrogen oxides

510131, 510159, A61K 748

Patent

active

055737862

ABSTRACT:
By reacting 1-5.5M nitric acid with from 45 to 170 mmol of primary C.sub.1 -C.sub.5 -alkanol per l of nitric acid, an improved preparation is obtained for the local treatment of changes in skin and mucous membrane and of infections of the skin and mucous membrane. The preparation comprises 1-5.5M nitric acid, not more than 170 mmol of C.sub.1 -C.sub.5 -alkanoic acid per l of solution, and nitrate reduction products in a concentration corresponding to from 0.1 to 6 mg of nitrite per ml of solution. The preparation is notable for a good activity and a low risk of side effects.

REFERENCES:
patent: 4595591 (1986-06-01), Mardi
European Drug Index, Second Edition, edited by Muller et al., 1992, p. 1096.
Heaton, et al., Clinical Pharmacology and Therapeutics, "The Revival of Nitric Acid for the Treatment of Anogenital Warts", vol. 54, No. 1, pp. 107-111 (1993).

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