Preparation for percutaneous administration

Details Preparation for percutaneous administration Preparation for percutaneous administration

1987-05-13

1988-08-23

Hollrah, Glennon H.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Web, sheet or filament bases; compositions of bandages; or...

424 81, 514386, A61K 970, A61K 31415, A61L 1503, A61F 1302

Patent

active

047659742

ABSTRACT:
A clonidine preparation for percutaneous administration comprising a support having provided thereon an active ingredient-containing layer is disclosed. The active ingredient-containing layer contains an acrylic polymer having a glass transition temperature of from -70.degree. C. to -10.degree. C. and pressure-sensitive adhesion at room temperature as a base, at least one of clonidine and clonidine hydrochloride as an active ingredient, and a decomposition inhibitor. The active ingredient can be stably maintained within the preparation without being decomposed, and, therefore, can be effectively released over a prolonged period of time.

REFERENCES:
patent: 3896789 (1975-07-01), Trancik
patent: 4390520 (1983-06-01), Nagai et al.
patent: 4409206 (1983-10-01), Stricker
patent: 4420470 (1983-12-01), Otsuka et al.
patent: 4552751 (1985-11-01), Inaka et al.
Derwent C82-891398 82.09.17 Nitto.
Derwent 85-285480 85.02.10 Nitto.
Derwent 85-131654 85.04.19 Nitto.

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