Preparation for oral hygiene

Details Preparation for oral hygiene Preparation for oral hygiene

1986-08-29

1988-01-12

Rose, Shep K.

Drug, bio-affecting and body treating compositions

Dentifrices

A61K 716

Patent

active

047191007

ABSTRACT:
A composition for oral hygiene with improved efficacy against dental plaque, said composition containing zinc aspartate and/or copper aspartate, preferably in an amount of 0.05 to 5% by weight based on the total weight of the composition.

REFERENCES:
patent: 4146607 (1979-03-01), Ritchey
patent: 4289755 (1981-09-01), Dhabbar
patent: 4325939 (1982-04-01), Shah
Hanke, Milton Theo., "Studies on the Local Factors in Dental Caries. I. Destruction of Plaques and Retardation of Bacterial Growth in the Oral Cavity", J. Amer. Den. Assn., vol. 27, No. (1940), pp. 1379-1393.
AADR Abstracts 1975, p. 117.
Literature Reference, vol. 59 (DI), p. 1827.
Afseth, John "Some Aspects of the Hynamics of Cu and Zn Retained in Plaque as Related to their Effect on Plaque pH", Scand J. Dent Res. 1983, vol. 91, pp. 169-174.
Afseth, John, "Accumulation of Cu and Zn in Human Dental Plaque in vivo", Caries Res. 17:310-314 (1983).
Saxer, U. P. et al, "Synergistic Antiplaque Effects of a Zinc Fluoride/Hexetidine Containing Mouthwash. A Review", HOA Vo. 27; 1-16; Aug. 1983.
Afseth, John et al, "Effect of Copper Applied Topically or in Drinking Water on Experimental Caries in Rats", Caries Res. 18:434-39 (1984).

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