Chemistry: molecular biology and microbiology – Carrier-bound or immobilized enzyme or microbial cell;... – Enzyme or microbial cell is immobilized on or in an organic...
Reexamination Certificate
2008-01-29
2008-01-29
Li, Q. Janice (Department: 1633)
Chemistry: molecular biology and microbiology
Carrier-bound or immobilized enzyme or microbial cell;...
Enzyme or microbial cell is immobilized on or in an organic...
C435S174000, C435S180000, C435S325000, C435S382000, C424S093100
Reexamination Certificate
active
07323323
ABSTRACT:
The invention relates to developments in the treatment of diabetes in mammals. Particularly it relates to a method of preparing a xenotransplantable porcine islet preparation capable upon xenotransplantation of producing porcine insulin in an appropriate recipient mammal, the method including or comprising the steps of:(I) harvesting the pancreas of piglets at or near full term gestation, and(ii) extracting pancreatic β islet cells from the harvested pancreas wherein the islets (at least at some stage in the performance of the method) are exposed to nicotinamide.Further, the invention relates to a method of encapsulation of a xenotransplantable porcine islet preparation, and transplantation of such a preparation, or a capsule containing such a preparation, into an appropriate recipient mammal.
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Basta Gusseppe
Calafiore Riccardo
Elliott Robert Bartlett
Diabell Pty Ltd.
Haynes and Boone LLP
Li Q. Janice
Moore Mark D.
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