Preparation and use of polyethylene glycol propionaldehyde

Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Blood proteins or globulins – e.g. – proteoglycans – platelet...

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10628723, 10628724, 10628725, 525515, 5303917, 530406, 530410, 568 41, 568494, 568613, C07K 308, C07C32114, C07C 4712, C07C 4310

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052527140

ABSTRACT:
A new polyethylene glycol derivative (PEG) having the property of not being destroyed by water and also being able to retain reactivity in water and selectively react with amine groups. Also provided is a process for modifying organic or polymer surfaces in water by connecting PEG derivatives to exposed amine groups which provides a process whereby there is efficient linking to organic or polymer surfaces in water by use of the PEG derivatives.

REFERENCES:
patent: 4002531 (1977-01-01), Roger
patent: 4029765 (1977-06-01), Hetting
patent: 4101380 (1978-07-01), Rubinstein et al.
patent: 4179337 (1979-12-01), Davis et al.
patent: 4791192 (1988-12-01), Nakagawa et al.
patent: 5080891 (1992-01-01), Saifer et al.
Veronese et al., J. Pharm. Pharmacol., vol. 35, pp. 757-758 (1983).

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