Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Particulate form
Patent
1994-07-20
1996-08-20
Page, Thurman K.
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Particulate form
424 91, 424 93, A61K 916, A61K 950
Patent
active
055476821
ABSTRACT:
Novel N-RES agents for use in vitro and in vivo medical and biological applications, such as, for example MRI and/or intravenous administration of pharmaceutical agents are described. The novel N-RES agents are prepared by coating inorganic core particles with a poly(acrylic acid)--poly(alkylene ether) graft copolymer. The resulting polymer-coated inorganic particle cores are useful as imaging agents, therapeutic agents or carriers having increased circulation time due to decrease uptake or recognition by the RES.
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Burkle Stephen E.
Carter Michelle J.
Chagnon Mark S.
Hamilton Tracy J.
Havelick, Jr. John
Benston, Jr. William E.
BioQuest, Incorporated
Page Thurman K.
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