Preparation and use of contrast agents

Organic compounds -- part of the class 532-570 series – Organic compounds – Heavy metal containing

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556 43, 556 52, 556 56, C07F 1100, C07F 900, C07F 700

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active

057171211

ABSTRACT:
A process for the preparation of multinuclear cluster compounds by reacting a metal carbonyl with iodine, and use of these clusters and clusters derived from them, in diagnostic imaging. Novel multinuclear cluster compounds are also disclosed.

REFERENCES:
Inorganic Chemistry, vol. 12, No. 10, Easton US, pp. 2356-2361, XP002021635, A.D. Westland et al. "Reactions of Halocarbonyls of Group VIB Elements.II Complexes of Molybdenum and Tungsten Containing Group VA Donors or Phenyl Isocynaide." (1973).
Chemical Abstracts, vol. 102, No. 24, Jun. 17, 1985, Columbus, Ohio, US; abstract No. 214063, Schaefer, Harald et al.: "Tungsten/iodine system", XP002021934, see abstract & Z. Anorg. Allg. Chem. (1984), 516, 196-200 CODEN: ZAACAB; ISSN: 0044-2313, 1984.
Schulz et al., Chemical Abstracts, vol. 73, No. 22, Chemical Abstract No. 115864j, p. 460 (1970).
Franolic et al., Journal of American Chemical Society, vol. 117, No. 31, pp. 8139-8153 (1995).

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