Preparation and use of a 195M-AU-containing liquid

Details Preparation and use of a 195M-AU-containing liquid Preparation and use of a 195M-AU-containing liquid

1980-04-16

1983-11-08

Kyle, Deborah L.

Compositions

Radioactive compositions

As a source of radiation or heat

250432PD, 423 25, 423 99, 423100, 424 1, G21G 408

Patent

active

044141459

ABSTRACT:
A method for preparing a .sup.195m Au-containing liquid is provided. In the method, .sup.195m Hg is adsorbed on an adsorption agent and then the daughter radioisotope .sup.195m Au is eluted from the adsorption agent with an eluant containing a gold-complexing agent. The adsorption agent comprises a mercury ion-binding material having a substantially stronger adsorption affinity for mercury ions than for gold ions.
Also disclosed are a radioisotope generator capable of producing a .sup.195m Au-containing liquid and a process for conducting a radiodiagnostic examination on a warm-blooded animal using a .sup.195m Au-containing liquid.

REFERENCES:
patent: 3317312 (1967-05-01), Kraus et al.
patent: 3785990 (1974-01-01), Benjamins et al.
patent: 3898044 (1975-08-01), Strecker et al.
patent: 3935098 (1976-01-01), Oda et al.
Lebowitz et al., "Radionuclide Generator Systems" Sem. in Nucl. Med., vol. 4, No. 3, (Jul.) 1974, pp. 257-268.
Gupta et al., "Ion Exchange Behavior of Mercury (II) . . . ", Nucl. Sci. Abs., vol. 27, Abs. #11668 (1973).
Halasz et al., "Micro Beads Coated with a Porous Thin Layer . . . ", Anal. Chem., 36(7), 1964, pp. 1178-1186.
Christensen et al., "Ion Binding by Synthetic Macrocyclic Compounds", Science, vol. 174, No. 4008 (Oct. 1971), pp. 459-467.

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