Preparation and use of...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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C514S318000, C514S333000, C546S113000, C546S276700, C546S289000

Reexamination Certificate

active

07071207

ABSTRACT:
This invention relates to 1,5,6,7-tetrahydropyrrolo[3,2-c]pyridine derivatives which have been found to suppress appetite and induce weight loss. The invention also provides methods for synthesis of the compounds, pharmaceutical compositions comprising the compounds, and methods of using such compositions for inducing weight loss and treating obesity and obesity-related disorders.

REFERENCES:
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patent: 6011044 (2000-01-01), Choi et al.
patent: 2002/0013336 (2002-01-01), Peter et al.
patent: EP-0725068 (1996-08-01), None
patent: 0043397 (2000-07-01), None
patent: 0101969 (2001-11-01), None
Nagai, et al., Studies on Phsychotropic Agents. II.I Synthesis of 1-Substituted-3-(ρ-fluorophenacyl)piperidines and the Related Compounds, Chem. Pharm. Bull., 25, 1911-1922 (1977).
Nagarajan, et al., Antiimplantation Agents: Part III-1,2-Diaryl-4,5-polymethylenepyrroles & 1,2-Diaryl-4oxo- & 1,2-Diaryl-4-hydroxy-4,5,6,7-tetrahydroindoles, Indian Journal of Chemistry, 24B, 98-111 (1985).

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