Preparation and purification of 4-(indazol-3-yl)phenols

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

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Reexamination Certificate

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07601847

ABSTRACT:
The present invention concerns processes for the production and purification of compounds of the formula:where R1-R10are as defined in the specification. Preferred processes of the invention utilize a lithium bis(trimethylsilyl)amide, lithium dicyclohexylamide, or potassium bis(trimethylsilyl)amide base and a R1—X alkylating agent where X is as described in the specification. An alcohol preferably is added to the product solution is used to promote crystallization of the desired product.

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