Preparation and application of scopolamine and chlorpromazine as

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

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514411, 514291, A61K 3154, A61K 3140, A61K 3144

Patent

active

055434070

ABSTRACT:
An empirical efficacy appears in the drug-withdrawal treatment of drug dependence with a novel drug-withdrawal scopolamine agent(DSA) which contains scopolamine hydrobromide as a subsidiary component. Each of the drugs may be used either combined as an injectable preparation or used integrately as separated injections for drug-withdrawal treatment.

REFERENCES:
patent: 4555397 (1985-11-01), Bachynsky
patent: 4746509 (1988-05-01), Haggiage et al.
patent: 5034400 (1991-07-01), Olney
patent: 5189064 (1993-02-01), Blum et al.
Chlorpromazine and Scopolamine in USP XXII, p. 293-294 and 1238-1239 (1990).
O'Brien, "Drug Abuse and Dependent", Cecil Textbook of Medicine, 19th ed., 47-55 (1992).
Weiner, "Atropine, Scopolamine, and Related Antimuscarinic Drugs", The Pharmacological Basis of Therapeutics, 6th ed., Goodman and Gilman Ed., 120-132, Chapter 7 (1980).
Gold et al., "Clonidine Blocks Acute Opiate-Withdrawal Symptoms", The Lancet, 599-601 (1978).

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