Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Patent
1989-06-13
1991-10-08
Wax, Robert A.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
435 91, 536 26, 536 27, 536 28, 436501, 436 94, C12P 1934, C12Q 768, C07H 1512, C07H 1700
Patent
active
050553933
ABSTRACT:
Compositions and methods are provided for determining the sex of Bovine embryos and fetuses employing male-specific oligonucleotides in nucleic acid probe hybridization assay methods to assay the genomic DNA of embryonic or fetal cells for the presence of male-specific sequences.
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patent: 4769319 (1988-09-01), Ellis et al.
Bondioli et al., "The Use of Male-Specific Chromosomal DNA Fragments to Determine the Sex of Bovine Preimplantation Embryos", Therigenology, 31:1, 1989, pp. 95-104.
Ellis et al., "Sex Determination of Bovine Embryos Using Male-Specific DNA Probes", Theriogeonology, 29:1, 1988, p. 242.
Herr et al., "Accuracy of a rapid Y-Chromosome-Detecting Bovine Embryo Sexing Assay", personal communication.
Herr et al., "Field Implementation of a Rapid Y-Chromosome-Detecting Bovine Embryo Sexing Assay", personal communication.
Handyside et al., "Biopsy of Human Preimplantation Embryos and Sexing by DNA Amplification", The Lancet, Feb. 18, 1989, pp. 347-349.
Kirszenbaum et al., "PCR Sexing Bovine Embryos Using Y Chromosome Specific Sequences", Journal of Cellular Biochemistry Abstracts, Supplement 13E, 1989, WH200, p. 293.
Leonard et al., "Sexing Bovine Embryos Using Y Chromosome Specific DNA Probe", Theriogenology, 27:1, 1987, p. 248.
Li et al., "Amplification and Analysis of DNA Sequences in Single Human Sperm and Diploid Cells", Nature, 35:29, 1988, pp. 414-417.
Gingeras Thomas R.
Kwoh Deborah Y.
Salk Institute Biotechnology Industrial Associates, Inc.
Steffe Eric
Wax Robert A.
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