Pregancy specific proteins applications

Details Pregancy specific proteins applications Pregancy specific proteins applications

1989-08-07

1992-12-08

Nucker, Christine M.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

514 12, 514 21, 4352402, 435244, 530395, 530397, 424583, A61K 3550, A61K 3702, C07K 1514

Patent

active

051698358

ABSTRACT:
At least seven genes have been identified which encode proteins generally identified as pregnancy specific protein (SP1), also known as pregnancy specific beta glycoprotein (PSBG). These genes have been found using human placental SP1 labelled cDNA in a number of mammalian species, including human, baboon, cow, sheep, goat, pig and rat, and non-mammalian species, including fish and bird. The genes are classified on the basis of their nucleotide sequence, structure, glycosylation sites, restriction enzyme mapping, and tissue of origin. Genes have been found in cells of human placenta origin (three groups); in intestinal cells; in cells of both testis and placental origin; in tissue of testis origin; and in HeLa cells. One clone encodes a SP1-like protein which is specifically found in placenta a

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