Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai
Reexamination Certificate
2006-04-04
2006-04-04
Wilson, James O. (Department: 1623)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Carbohydrate doai
C514S649000, C514S227800, C514S231500, C514S266200, C514S300000, C514S338000, C514S043000, C514S025000, C514S561000, C514S461000, C514S557000, C536S017400, C536S004100, C562S507000, C560S122000
Reexamination Certificate
active
07022678
ABSTRACT:
In accordance with the present invention, there is provided pregabalin lactose conjugate compounds.Also provided as part of the present invention is a novel method of central nervous system disorders or diseases including seizure disorders, pain, depression, anxiety, sleep disorders, consumptive disorders, psychosis, tardive dyskinesia, Huntington's disease, or Parkinson's disease in a subject by administering to the subject a pharmaceutically effective amount of a pregabalin lactose conjugate.
REFERENCES:
patent: 6197819 (2001-03-01), Silverman et al.
patent: 6359005 (2002-03-01), Pande
patent: 6488964 (2002-12-01), Bruna et al.
patent: 6544998 (2003-04-01), Mylari
Wirth et al. “Maillard reaction of lactose and fluoxetine hydrochloride, a secondary amine”, J. Pharm. Sci., vol. 87, No. 1, pp. 31-39, 1998.
Maillard, “Chimie Organique—Action des acides amines sur les sucres; formation des melanoidines par voie methodique”,Comptes Rendus, vol. 154, No. 2, 1912, pp. 66-68.
Colaco et al., “Pharmaceutical Formulation Instability and the Maillard Reaction”,Chimica Oggi, vol. 14, 1996, pp. 32-37.
Wirth et al., “Maillard Reaction of Lactose and Fluoxetine Hydrochloride, a Secondary Amine”,J. Pharm. Sci., vol. 87, No. 1, 1998, pp. 31-39.
Hodge, “The Amadori Rearrangement”,Advances in Carbohydrate Chemnistry, 1955, pp. 169-205.
Colaco C A L S, et al., “Pharmaceutical Formulation Instability and the Maillard Reaction”, Chimica OGGI, Teknoscienze, Milano, IT, vol. 17, pp. 32-37 (Jul. 1996).
Field, M.J., et al., “Gabapentin and Pregabalin, But Not Morphine and Amitriptyline, Block Both Static and Dynamic Components of Mechanical Allodynia Induced by Streptozocin in the Rat”, Pain, Elsevier Science Publishers, Amsterdam, NL, vol. 80, pp. 391-398 (1999).
Kumar, V., et al., “Maillard Reaction and Drug Stability”, Maillard Reactions in Chemistry, Food and Health, p. 20-27 (1994).
Lovdahl, Michael J., et al., “Synthesis and characterization of pregabalin lactose conjugate degradation products”, J. of Pharma and Biomed Analysis, vol. 28:5, p. 917-924 (Jun. 2002).
Maillard, L.C., “Action des acides amines sur les sucres; formation des melanoides par voie methodique”, Comptes Rendus Des Seances De L'Academie Des Sciences, vol. 154, pp. 66-68 (1912).
Taylor, C.P., et al., “Potent and Sterospecific Anticonvulsand Activity of 3-Isobutyl Gaba Relates to In Vitro Bindings at a Novel Site Labeled by Tritiated Gabapentin”, Epilepsy Research, Elsevier Science Publishers, Amsterdam, NL, vol. 14:1, pp. 11-15 (1993).
Wirth, D.D., et al., “Maillard reaction of lactose and fluoxetine hydrochloride, a secondary amine”, Journal of Pharmaceutical Sciences, vol. 87:1, p. 31-39 (Jan. 1998).
Hurley Timothy Robert
Lovdahl Michael James
Tobias Brian
Ashbrook Charles W.
DeBenedictis Karen
Khare Devesh
Kurlandsky David R.
Warner-Lambert & Company
LandOfFree
Pregabalin lactose conjugates does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Pregabalin lactose conjugates, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Pregabalin lactose conjugates will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3548458