Surgery – Respiratory method or device – Means for mixing treating agent with respiratory gas
Patent
1997-02-24
1998-11-03
Asher, Kimberly L.
Surgery
Respiratory method or device
Means for mixing treating agent with respiratory gas
12820014, 12820323, A61M 1508, A61M 1610, A61M 1100
Patent
active
058294350
ABSTRACT:
A device, drug package and methodology for using such to generate an aerosol by moving a flowable formulation through a low resistance filter and then through a nozzle comprised of a porous membrane are disclosed. The package is comprised of a collapsible wall portion that forms a container for holding a liquid formulation which container has an opening covered by a cover portion comprising a nozzle. The membrane pores of the nozzle have a size in the range of 0.25 to 6 microns, preferably 0.5 to 6 microns. A low resistance filter, which is positioned between the flowable formulation and the nozzle, includes openings that are the same size as or smaller than the pores of the nozzle's porous membrane but includes the openings in an amount and density such that flowable formulation flows through the filter with less resistance than when the formulation moves through the porous membrane. Thus, the filter does not significantly increase the amount of pressure needed to aerosolize the formulation, prevents clogging of the porous membrane of the nozzle by any undesirable particles that may be in the formulation, prevents delivery of any such undesirable particles to the patient, and thereby improves the homogeneity of the aerosol formulation delivered to the patient, as well as the consistency and reproducibility of the aerosolized dose created.
REFERENCES:
patent: 1063406 (1913-06-01), Witt
patent: 3658059 (1972-04-01), Steil
patent: 3934585 (1976-01-01), Maurice
patent: 4677975 (1987-07-01), Edgar et al.
patent: 5404871 (1995-04-01), Goodman et al.
patent: 5419315 (1995-05-01), Rubsamen
patent: 5450336 (1995-09-01), Rubsamen et al.
patent: 5497763 (1996-03-01), Lloyd et al.
patent: 5497944 (1996-03-01), Weston et al.
patent: 5544646 (1996-08-01), Lloyd et al.
patent: 5647349 (1997-07-01), Ohki et al.
Cipolla David
Farr Stephen
Gonda Igor
Rubsamen Reid
Aradigm Corporation
Asher Kimberly L.
Bozicevic Karl
Francis Carol L.
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