Prednisone microencapsulated granules

Details Prednisone microencapsulated granules Prednisone microencapsulated granules

1989-07-26

1990-10-30

Page, Thurman K.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Capsules

424400, 424439, 424462, 424470, 424493, 424494, 424495, 424497, 424498, A61K 958, A61K 962, A61K 926, A61K 916

Patent

active

049667700

ABSTRACT:
The invention disclosed is prednisone microencapsulated granules with activity densities greater than about 0.030 g/ml. These granules are unusually small, having diameters less than about 1000 microns. The granules are particularly useful in hand-held flowable material dispensers. A process for manufacturing such granules is also disclosed.

REFERENCES:
patent: 4083949 (1978-04-01), Benedict
patent: 4138475 (1979-02-01), McAinsh et al.
patent: 4166800 (1979-09-01), Hsiao
patent: 4193985 (1980-03-01), Bechgaard et al.
patent: 4261970 (1981-04-01), Ogawa et al.
patent: 4263273 (1981-04-01), Appelgren et al.
patent: 4341759 (1982-07-01), Bogentoft et al.
patent: 4508702 (1985-04-01), Hsiao
patent: 4513019 (1985-04-01), Brancq et al.
patent: 4587118 (1986-05-01), Hsiao
patent: 4874613 (1989-10-01), Hsiao
Porter, S. C. et al., The Effect of Choice of Process in Drug Release from Non-Pareils Film Coated with Ethyl Cellulose, Proceed. Intern. Symp. Control Rel. Bract. Makr., 12, 41-42, (1985).
Baker, R., Analysis of Oral Dosage Form Patents, 1939 to 1985.

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