Prednisolone derivatives

Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal

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2603971, 26039745, C07J 500

Patent

active

045115117

ABSTRACT:
Novel prednisolone derivatives modified at C-17,C-20 and/or C-21 positions. Many of the compounds are anti-inflammatory agents which do not significantly suppress the pituitary-adrenal axis.

REFERENCES:
patent: 3944577 (1976-03-01), Laurent et al.
Solimon, M. R. I. et al. "6th Ann. Clin. Symp. Proc. Res. Cline. Application Corticoids", Proceedings (Dec. 1981), a paper titled New Antiinflammatory Steroids: Steroid-21-oate Esters.
Heiman et al., "Steroids", vol. 38, No. 4, (1981), p. 2799.
Lee et al., (2), "Science", Feb. 1982, vol. 215, pp. 989-991.
Lee et al., "Research Communications in Chemical Pathology and Pharmacology", vol. 27, No. 3, (1980), p. 611.
Soliman et al., "Research Communications in Chemical Pathology and Pharmacology", vol. 33, No. 2, Aug. 1981.

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