Predicting predisposition to osteoporosis

Details Predicting predisposition to osteoporosis Predicting predisposition to osteoporosis

1985-09-27

1988-04-26

Hollrah, Glennon H.

Drug, bio-affecting and body treating compositions

In vivo diagnosis or in vivo testing

Magnetic imaging agent

G01N 3348

Patent

active

047403640

ABSTRACT:
A method of providing a diagnostic indicia which is predictive of the risk of a non-osteoporotic human being contracting osteoporosis as a consequence of being in a long-term hormonally agonadal state, which comprises the steps of determining the average ratio of calcium to creatinine in the urine or in the blood of that person, during a period when the person is ingesting only foodstuff sources of calcium and vitamin D, while in a hormonally gonadal state, and also while in a hormonally agonadal state; determining the magnitude of the difference in the ratio obtained in the latter state compared to the former state, a large difference being predictive of a high risk of that person contracting osteoporosis.

REFERENCES:
Abbasi et al., JAMA, vol. 255, No. 12, pp. 1600-1604, Predicting the Piedisposition to Osteoporosis (1986).
Hodgen et al I, Amer. J. N. Obsterics & Gynecology, vol. 127, No. 6, pp. 581-584 (1977).
Erb et al, J. Animal Science, vol. 30, No. 1 (1970).
Urago; Acta Pat. Hol. Jpn, vol. 32, No. 5, pp. 759-770 (1982).
Hodgen et al II, J. Animal Science, vol. 26, No. 3 (1967).
Miller et al, Calcif. Tissue Int. (38) pp. 62-65 (1986).

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