Precursor indicator compositions

Details Precursor indicator compositions Precursor indicator compositions

1979-09-06

1981-12-22

Wiseman, Thomas G.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

435 15, 435 18, 435 19, 435 21, 435 23, 435 24, 435 28, 435805, 23230B, C12Q 100, C12Q 148, C12Q 134, C12Q 144

Patent

active

043071880

ABSTRACT:
A composition, test device, method of making a test device and process for determination of an analyte in a liquid sample are disclosed. More particularly, there is provided a composition for detecting an analyte in a liquid sample comprising an analyte-responsive component and an indicator composition having a plurality of components comprising at least one nonresponsive precursor component and at least one component effective in a liquid milieu to alter said precursor component so as to release at least one substance effective to permit said indicator composition, in combination with said analyte-responsive component, to produce a detectable response to said analyte. The composition can optionally be incorporated with a carrier to form a device.

REFERENCES:
patent: Re29498 (1977-12-01), Meiattini
patent: 4119405 (1978-10-01), Lam
patent: 4129417 (1978-12-01), White
Bergmeyer, "Determination of Concentration of Metabolites (End-Point Methods)", Methods of Enzymatic Analysis, vol. 1, Academic Press, N.Y., (1974), pp. 103-120.

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