Preclinical SPECT system using multi-pinhole collimation

Radiant energy – Invisible radiant energy responsive electric signalling – With or including a luminophor

Reexamination Certificate

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Reexamination Certificate

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07579600

ABSTRACT:
A preclinical nuclear imaging detector system, including a gantry and one or more detector assemblies, each including a scintillator configured to interact with radiation emanating from a target test object being imaged and at least one pinhole collimator, having one or more pinhole apertures formed therein. The pinhole collimator is disposed between the target object and the scintillator, wherein a distance between the pinhole aperture and the scintillator is selected as a function of the number of pinhole apertures provided in the collimator and to optimize one of sensitivity or spatial resolution, such that the one or more pinhole apertures collectively project a unitary minified radiation image of the target object onto the scintillator. Further, one or more photosensors are optically coupled to the scintillator to receive interaction events from the scintillator.

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Lackas et al., T-SPECT: A Novel Imaging Technique for Small Animal Research, IEEE Transactions on Nuclear Science, vol. 52, No. 1, Feb. 2005, pp. 181-187.

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