Stock material or miscellaneous articles – Coated or structually defined flake – particle – cell – strand,... – Particulate matter
Reexamination Certificate
2005-08-02
2008-11-04
Le, H. T (Department: 1794)
Stock material or miscellaneous articles
Coated or structually defined flake, particle, cell, strand,...
Particulate matter
C427S222000
Reexamination Certificate
active
07445844
ABSTRACT:
An improved method of making a series of bead or microsphere or particle populations characterized by subtle variation in a proportion or ratio of at least two fluorescent dyes distributed within a single bead of each population is provided. These beads, when excited by a single excitation light source are capable of giving off several fluorescent signals simultaneously. A set containing as many as 64 distinct populations of multicolored, fluorescent beads is provided and when combined with analytical reagents bound to the surface of such beads is extremely useful for multiplexed analysis of a plurality of analytes in a single sample. Thus, methods of staining polymeric particles, the particles themselves, and methods of using such particles are claimed.
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Chandler Don J.
Chandler Van S.
Lambert Beth A.
Phipps Stacie L.
Reber Janet J.
Daffer McDaniel LLP
Huston Charles D.
Le H. T
Lettang Mollie E.
Luminex Corporation
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