Precipitation of protein

Chemistry: physical processes – Physical processes – Crystallization

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Details

260112B, 23923, G01N 3102, G01N 33161

Patent

active

041712048

ABSTRACT:
A method for analyzing blood serum or plasma wherein the blood serum or plasma is treated with about 1.4 or more volumes of acetonitrile, propionitrile, tetrahydrofuran or mixtures thereof to precipitate proteins and to provide a supernatant. The separated supernatant is subsequently examined for a component of interest.

REFERENCES:
patent: 2726235 (1955-12-01), Hill
patent: 3301692 (1967-01-01), Karjala
patent: 3672954 (1972-06-01), Grippa
patent: 3847889 (1974-11-01), Fryklund
patent: 3893991 (1975-07-01), Fekete
patent: 4100149 (1978-07-01), Meiller
Neurath, H. and Bailey, K. (Eds.), "The Proteins," Vol. I, Part B, Academic Press, Inc., N.Y., 1953, Chapt. 9, Putnam, F. W. (Ed.), "Protein Denaturation", pp. 821-830.
Putnam, F. W. (Ed.), "The Plasma Proteins", Vol. I, Academic Press, Inc., N.Y., 1960, Chapt. 2, Pennell, R. B. (Ed.), "Fractionation and Isolation of Purified Components by Precipitation Methods", pp. 5-50.

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