Precipitation of one or more active compounds in situ

Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Implant or insert

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Details

424422, 424423, 514818, 514817, A61K 908

Patent

active

059165839

ABSTRACT:
The present invention relates to an injectable solution for administration of one or more active compounds. According to the invention the active compound, which is in its neutral form, is dissolved in a biologically acceptable solvent whereby the active compound by administration precipitates, forming a solid phase of the solution in situ. Thus, said solution, which is easy to sterilize, is acting like a suspension when injected.

REFERENCES:
patent: 4259331 (1981-03-01), Armstrong
patent: 4268495 (1981-05-01), Muxfeldt et al.
patent: 5051257 (1991-09-01), Pietronigro
patent: 5096926 (1992-03-01), Fiorini et al.
patent: 5324519 (1994-06-01), Dunn et al.
Bourget et al., "Factors Influencing Precipitation . . . " J.Clin.Pharm. and Thera. (1990) 15, 197-204.
Sinclair et al., "Topical Anesthesia with Lidocaine . . . " Anesthesiology, 68: 895-901, 1988.
Hussain et al., "Injectable Suspensions for Prolonged . . . " Drug Devel. and Ind. Pharm., 17(1), 67-76 (1991).
Holst et al., "Effects of Lidocaine aerosol . . . " Acta.Anaesthesiol.Scand. 1992: 36: 112-114.
Hoefflin, "Marcaine Spray" Plast.Reconstr.Surg., 1989: 84, 543.
J.A. Fonte Itaracs, "Bupivacaine Squirting" Ann. R. Coll. Surg. Engl. 71, 1989, 72.
Benzon et al., "The Effect of Polyethylene Glycol . . . " Anesth. Analg., 1987; 66; 553-559.

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