Pre-storage filtration of platelets

Details Pre-storage filtration of platelets Pre-storage filtration of platelets

1990-02-12

1992-02-18

Dawson, Robert A.

Liquid purification or separation

Processes

Separating

210787, 210806, 210206, 2102571, 604406, 604410, B01D 3315

Patent

active

050891464

ABSTRACT:
Filtration of white blood cells (WBCs) directly from platelet rich plasma (PRP) rather than from subsequently made platelet concentrates (PC). Earlier filtration is effective at removing most WBCs with minimal platelet loss and permits storage of platelets for at least 5 days. The filtration is preferably done with a closed, ready-to-use system comprising a WBC filter disposed between a first blood bag and at least two empty secondary bags. A fourth bag may be included in the closed system to contain a platelet additive solution. System can remove at least 95% of the WBCs with less than 10% loss in platelets. In very preferred embodiments at least 99.5% of the original WBCs are removed by filtration prior to platelet storage.

REFERENCES:
patent: 4344560 (1982-08-01), Iriguchi et al.
patent: 4447415 (1984-03-01), Rock et al.
patent: 4596657 (1986-06-01), Wisdom
patent: 4767541 (1988-08-01), Wisdom
patent: 4855063 (1989-08-01), Carmen et al.
patent: 4880548 (1989-11-01), Pall et al.
patent: 4943287 (1990-07-01), Carmen
patent: 4985153 (1991-11-01), Kuroda et al.
patent: 4997577 (1991-03-01), Stewart

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