Pre-farrowing pregnant sow piglet colibacillosis vaccines and pr

Drug – bio-affecting and body treating compositions – Whole live micro-organism – cell – or virus containing – Genetically modified micro-organism – cell – or virus

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424 87, A61K 3902, A61K 3940

Patent

active

040535843

ABSTRACT:
Piglet colibacillosis vaccine for intramuscular or subcutaneous administration to pregnant sows comprising cell-free heat labile (LT) E. coli enterotoxin with an adjuvant and the method for preventing piglet colibacillosis consisting in administering said vaccine to pregnant sows from 3 to 6 weeks before farrowing.

REFERENCES:
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patent: 3127318 (1964-03-01), Eversole et al.
patent: 3149036 (1964-09-01), Woodhour et al.
patent: 3376198 (1968-04-01), Petersen et al.
Miniats et al., Can. Vet. J., 8:260-268 (1967) "Antibody Response of Young Pigs to Vaccination with E. Coli".
Kohler et al., Am. J. Vet. Res., 29:1419-1428 (July, 1968) "Serological Response of Swine to Escherichia Coli Antigens".
Sojka, Vet. Bull., 41(7):509-522 (July, 1971) "Entoric Diseases in New-Born Piglets, Calves and Lambs due to Escherichia Coli Infection".
Smith, et al., J. Med. Microbiol, 3:387-401 (1970) "The Relationship between Two Apparently Different Enterotoxins Produced by Enteropathogenic Strains of Escherichia Coli of Porcine Origin".
Gyles et al., J. Infect. Diseases, 120(4):419-426 (Oct. 1969) "A Heat-Labile Enterotoxin from Strains ofEscherichia Coli Enteropathogenic for Pigs".

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