Pre-electrophoretic nucleic acid hybridization

Details Pre-electrophoretic nucleic acid hybridization Pre-electrophoretic nucleic acid hybridization

1984-07-25

1988-01-26

Marantz, Sidney

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving nucleic acid

204 1T, 436501, C12Q 168

Patent

active

047216689

ABSTRACT:
This invention provides a method of detecting nucleic acid molecules employing cRNA probes in a pre-electrophoretic hybridization procedure. In addition to detecting the presence of nucleic acids an additional embodiment of the invention permits a determination of the size of said nucleic acids to be made.

REFERENCES:
patent: 4563417 (1986-01-01), Albarella et al.
Lewin (1983), In: Genes pp. 40-42, 51-52.
Noyes et al. (1975), Cell 5: 301-310.
Harris et al. (1978) Biochemistry 17(16): 3250-3256.
Vieira et al. (1982) Gene 19: 259-268.
Southern (1975), J. Mol. Biol 98: 503-517.
Alwine et al. (1977), Proc. Nat'l. Acad. Sci. 74(12): 5350-5354.
Britten et al. 1968), Sci. Am. 222(4): 24-31.
Maxam et al. (1977), Proc. Nat'l Acad. Sci. 74(2): 560-564.

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