Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai
Reexamination Certificate
2006-03-07
2006-03-07
Tate, Christopher R. (Department: 1654)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Peptide containing doai
Reexamination Certificate
active
07008927
ABSTRACT:
The preparation for intranasal administration comprising D-alanyl-3-(naphthalen-2-yl)-D-alanyl-L-alanyl-L-tryptophyl-D-phenylalanyl-L-lysinamide (pralmorelin) and/or an acid addition salt thereof as an active ingredient and water permits a marked increase in the in vivo absorption of pralmorelin and hence provides adequate efficacy even if it is administered in a small dose at a time. The preparation also allows pralmorelin to be dissolved in an increased amount, so it can be formulated pharmaceutically with great ease. It also high stability over time.
REFERENCES:
patent: 5776901 (1998-07-01), Bowers et al.
patent: 2004/0014671 (2004-01-01), Murata et al.
patent: 080879 (1983-06-01), None
patent: 0 301 392 (1989-02-01), None
patent: 490549 (1992-06-01), None
patent: 724885 (1996-08-01), None
patent: 63-303931 (1988-12-01), None
patent: 7-278015 (1995-10-01), None
patent: 10-45619 (1998-02-01), None
patent: WO 99/62539 (1999-12-01), None
patent: WO 01/97831 (2001-12-01), None
Johansen, P.B., et al (1998) Xenobiotica vol. 28, No. 11, p. 1083-1092.
Pihoker, C., et al (1997) J. Endocrinol. vol. 155, No. 1, pp. 79-86.
Pihoker, C., et al (1995) J. Clin. Endocrinol. Metabolism. vol. 80, No. 10, pp. 2987-2992.
Kaji, H., et al (1995) Hormone to Rinshou (Hormone and Clinic) vol. 43, No. 1, pp. 57-60 (with a partial English translation).
Vora, J., et al (1993) Journal of Controlled Release vol. 24, pp. 193-200.
Chan, R., et al (1988) Clinical Pharmacology & Therapeutics 44(3) pp. 275-282.
Dua, R., et al (1997) International Journal of Pharmaceutics, 147(2) pp. 233-242.
Patent Abstracts of Japan, Publication No. 2002053489, published Feb. 19, 2002. Doi Naomi, “Muscle Pill/Medicine for Preventing/Treating Muscular Decay.” .
Kato Yasutomi
Kogetsu Hirokuni
Maruyama Kiyoshi
Ochiai Akiko
Audet Maury
Kaken Pharmaceutical Co. Ltd.
Nixon & Peabody LLP
Tate Christopher R.
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