Pradimicin compounds

Details Pradimicin compounds Pradimicin compounds

1992-08-14

1994-08-16

Brown, Johnnie R.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

514 33, 514 34, 536 64, 536 172, 536 181, A61K 3170, C07H 1524

Patent

active

053387287

ABSTRACT:
Disclosed are novel pradimicin compounds which possess antifungal activity and, preferably, improved water solubility. The compounds of the invention are prepared by modifying the 4'-amino or 4'-alkylamino moieties of known pradimicin compounds.

REFERENCES:
patent: 4870165 (1989-09-01), Oki et al.
patent: 4960755 (1990-10-01), Nishio et al.
patent: 4973673 (1990-11-01), Sawada et al.
patent: 4990497 (1991-02-01), Oki et al.
patent: 4992425 (1991-02-01), Nishio et al.
patent: 5053395 (1991-10-01), Nishio et al.
patent: 5061624 (1991-10-01), Sawada et al.
patent: 5091418 (1992-02-01), Sawada et al.
patent: 5110960 (1992-05-01), Oki et al.
patent: 5114857 (1992-05-01), Sawada et al.
Berge, et al, "Pharmaceutical Salts," Journal of Pharmaceutical Sciences, Jan. 1977, 66(1) pp. 1-19.
Oki, et al., "Pradimicin, A Novel Class of Potent Antifungal Antibiotics," J. Antibiotics, 1988, 41, 1701-1704.
Tsunakawa, et al., "The Structures of Pradimicins A, B, and C: A Novel Family of Antifungal Antibiotics," J. Org. Chem., 1989, 54, 2532-2536.
Sawada, et al., "New Antifungal Antibiotics Pradimicins FA-1 and FA-2: d-Serine Analogs of Pradimicins A and C," J. Antibiotics, 1990, 43, 1223-1229.
Takeuchi, et al., "New Antifungal Antibiotics, Benanomicins A and B From an Actinomycte," J. Antibiotics, 1988, 41, 807-811.
Gomi, et al., "The Structures of New Antifungal Antibiotics," J. Antibiotics, 1988, 41, 1019-1028.

Affiliated with

Also associated with

Rating

Pradimicin compounds does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Pradimicin compounds, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Pradimicin compounds will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-951921