Practical synthesis of benzoxazinones useful as HIV reverse tran

Organic compounds -- part of the class 532-570 series – Organic compounds – Chalcogen in the nitrogen containing substituent

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C07D26518

Patent

active

061472107

ABSTRACT:
The present invention describes novel methods for the synthesis of benzoxazinone compounds which are useful as human immunodeficiency virus (HIV) reverse transcriptase inhibitors. The benzoxazinone of the formula: is particularly effective in the treatment of HIV.

REFERENCES:
patent: 5426230 (1995-06-01), Douglas et al.
patent: 5519021 (1996-05-01), Young et al.
patent: 5608062 (1997-03-01), Doller et al.
patent: 5922864 (1999-07-01), Frey et al.
Tucker et al. (1994) J. Med. Chem. 37: p. 2437-2444.
Karlsson et al. (1989) Tetrahedron Letters, vol. 30, No. 20: p. 2653-2656.
Houpis et al. (1994) Tetrahedron Letters, vol. 35, No.37: p. 6811-6814.
Hutchins et al. (1973) Journal of the Am Chemical Society, vol. 95:11. p. 3786-3790.
Douglas et al. (1994) Tetrahedron Letters, vol. 35, No. 37: p. 6807-6810.
Okabe et al. (1995) Tetrahedron, vol. 51, No. 7: p. 1861-1866.
Young et al. Antimicrobial Agents & Chemotherapy, Dec. 1995: p. 2602-2605.
Reuter et al. (1994) Tetrahedron Letters, vol. 35, No. 28: p. 4899-4902.
Reed et al. (1988) Tetrahedron Letters, vol. 29, No. 45: p. 5725-5728.
Berger et al. (1993) Heterocycles, vol. 36, No. 9: p. 2051-2058.
Masatomo Iwao, (1994) Heterocycles, vol. 38, No. 1: p. 45-50.
Cho et al. (1991) J. Org. Chem, vol. 56: p. 7288-7291.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Practical synthesis of benzoxazinones useful as HIV reverse tran does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Practical synthesis of benzoxazinones useful as HIV reverse tran, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Practical synthesis of benzoxazinones useful as HIV reverse tran will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-2066594

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.