Chemistry: molecular biology and microbiology – Enzyme – proenzyme; compositions thereof; process for... – Hydrolase
Reexamination Certificate
2007-11-13
2007-11-13
Spector, Lorraine (Department: 1646)
Chemistry: molecular biology and microbiology
Enzyme , proenzyme; compositions thereof; process for...
Hydrolase
C435S183000, C530S350000, C530S402000, C530S387100, C536S023200
Reexamination Certificate
active
10131837
ABSTRACT:
The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
REFERENCES:
patent: 5536637 (1996-07-01), Jacobs
patent: 2003/0207434 (2003-11-01), Baughn et al.
patent: 1 130 094 (2001-09-01), None
patent: WO 00/11015 (2000-03-01), None
patent: WO 01/25444 (2001-04-01), None
patent: 01/53455 (2001-07-01), None
patent: WO 01/55358 (2001-08-01), None
Lian et al., Genomic and proteomic analysis of the myeloid differentiation program, Blood 98(3):513-524, Aug. 1, 2001.
Haynes et al., Proteome analysis: Biologica assay or data archive, Electrophoresis, 19:1862-1871, 1998.
Hu et al., Analysis of genomic and proteomic data using advanced literature mining, J. Proteome Res., 2:405-412, Jun. 2003.
Fessler et al., A genomic and proteomic analysis of the activation of the human neutrophil by lipopolysaccharide and its mediation by p38 mitogen-activated protein kinase, J. Biol. Chem. 277(35):31291-31302, Aug. 30, 2002.
GenBank Database AB046041, Macaca fascicularis brain cDNA, Osada et al. accessed Jan. 31, 2005, Jul. 18, 2000.
Saito-Hisaminato et al., Genome-wide profiling of gene expression in 29 normal human tissues with a cDNA microarray, DNA Res., 9:35, 2002.
Gygi et al., Correlation between protein and mRNA abundance in yeast, Mol. Cell. Biol., 19(3):1720-1730, Mar. 1999.
Sagynaliev et al., Web-based data warehouse on gene expression in human colorectal cancer, Proteomics, 5:3066-3078, Aug. 2005.
Bustin et al., The value of microarray techniques for quantitative gene profiling in molecular diagnostics, Trends in Mol. Med., 8(6):269-272, 2002.
Greenbaum et al., Comparing protein abundance and mRNA expression levels on a genomic scale, Genome Biol. 4:117.1-117.8, 2003.
Anderson et al., A comparison of selecte mRNA and protein abundances in human liver, Electrophoresis 18:533-537, 1997.
Haviv et al., DNA microarray for assessing ovarian cancer gene expression, Mol. Cell. Endocrinol. 191:121-126, 2002.
Klein et al. Selection for Genes Encoding Secreted Proteins and Receptors.Proc. Natl. Acad. Sci., 93:7108-7113 (1996).
Database Search. DNA Sequence Alignments [BLASTN 2.2.1 [Jul. 12, 2001], NCBI].
Database Search, Protein Sequence Alignments [BLASTP 2.2.1 [Jul. 12, 2001], NCBI].
Golub, T.R., et al., “Molecular Classification of Cancer: Class Discovery and Class Prediction by Gene Expression Monitoring,”Science—285:531-537 (1999).
Hegde, P., et al., “A Concise Guide to cDNA Microarray Analysis,”BioTechniques—29(3):548-562 (2000).
Quackenbush, J., “Microarray Data Normalization and Transformation,”Nature Genetics Supplement—32:496-501 (2002).
Wen, W., et al., “Comparison ofTP53Mutations Identified by Oligonucleotide Microarray and Conventional DNA Sequence Analysis1,”Cancer Research—60:2716-2722 (2000).
MAQC Consortium, “The MicroArray Quality Control (MAQC) Project Shows Inter- and Intraplatorm Reproducibility of Gene Expression Measurements,”Nature Biotechnology—24(9):1151-1161 (2006).
Abe, N., et al., “An Increased High-Mobility Group A2 Expression Level is Associated with malignant Phenotype in Pancreatic Exocrine Tissue,”Br J Cancer—89(11):2104-9 (2003) Abstract.
Ando, M., et al., “Selective Apoptosis of Natural Killer-Cell Tumours by I-Asparaginase,”Br J Haematol.,—130(6):860-8 (2005) Abstract.
Barnes, V.L., et al., “Expression of Embryonic Fibronectin Isoform EIIIA Parallels Alpha-Smooth Muscle Actin In Maturing and Diseased Kidney,”J Histochem Cytochem.—47(6):787-98 (1999) Abstract.
Blaschke, V., et al., “Rapid Quantitation of Proinflammatory and Chemoattractant Cytokine Expression in Small Tissue Samples and Monocyte-Derived Dendritic Cells: Validation of a New Real-Time RT-PCR Technology,”J Immunol Methods.—246(1-2):79-90 (2000) Abstract.
Buckley, A.R., et al., “Butyrate-Induced Reversal of Dexamethasone Resistance in Autonomouse Rat Nb2 Lymphoma Cells,”Apoptosis.—2(6):518-28 (1997) Abstract.
Caberlotto, L. et al., “Alterations in Neuropeptide Y Levels and Y1 Binding Sites in the Flinders Sensitive Line Rats, A Genetic Animal Model of Depression,”Neurosci Lett.—265(3):191-4 (1999) Abstract.
Caberlotto, L., et al., “Neurokinin 1 Receptor and Relative Abundance of the Short and Long Isoforms in the Human Brain,”Eur J Neurosci.—17(9):1736-46 (2003) Abstract.
Chol, D., et al., “Characterization of Cyclin D2 Expression in Human Endometrium,”J Soc Gynecol Investig.—9(1):41-6 (2002) Abstract.
Couvelard, A., et al., “Human Chorionic Gonadotrophin Beta Expression in Malignant Barrett's Oesophagus,”Virchows Arch.—445(3):279-84 (2004) Abstract.
Dagenals, A., et al., “Downregulation of EnaC Activity and Expression by TNF-Alpha in Alveolar Epithelial Cells,”Am J. Physio Lung Cell Mol Physiol.—286(2):L301-11 (2004) Abstract.
De Boer, C.J., et al., “Involement of the CCNDI Gene in Hairy Cell Leukemia,”Ann Oncol.—7(3):251-6 (1996) Abstract.
Debieve, F., et al., “Inhibin and Activin Production and Subunit Expression in Human Placental Cells Cultured in Vitro,”Mol Hum Reprod.—6(8):743-9 (2000) Abstract.
Dong, Z., et al., “Expression of Membrane-Type Matrix Metalloproteinases 4, 5, and 6 in Mouse Corneas Infected withP. aeruginosa,” Invest Opthalmol Vis Sci—42(13):3223- (2001) Abstract.
Duchrow, M., et al., “Assessment of Proliferative Activity in Colorectal Carcinomas by Quantitative Reverse Transcriptase-Polymerase Chain Reaction (RT-PCR),”Cancer Invest.—19(6):588-96 (2001) Abstract.
Dyer, J., et al., “Molecular Characterisation of Carbohydrate Digestion and Absorption in Equine Small Intestine,”Equine Vet J.—34(4):349-58 (2002) Abstract.
Egwuagu, C.E., et al., “Suppressors of Cytokine Signaling Proteins are Differentially Expressed in Th1 and Th2 Cells: Implications for Th Cell Lineage Commitment and Maintenance,”J Immunol.—168(7):3181-7 (2002) Abstract.
El-Ghrably, I.A., et al., “Intravitreal Invading Cells Contribute to Vitreal Cytokine Milieu in Proliferative Vitreoretinopathy,”Br J Opthalmol.—85(4):461-70 (2001) Abstract.
Eleore, L., et al., “Modulation of the Glutamatergic Receptors (AMPA and NMDA) and of Glutamate Vesicular Transporter 2 in the Rat Facial Nucleus after Axotomy,”Neuroscience—136(1):147-60 (2005) Abstract.
Forsberg, H., et al., “Altered Levels of Scavenging Enzymes in Embryos Subjected to a Diabetic Environment,”Free Radic Res.—24(6):451-9 (1996) Abstract.
Freyschuss, B., et al., “Induction of the Estrogen Receptor by Growth Hormone and Glucocorticoid Substitution in Priminary Cultures of Rat Hepatocytes,”Endocrinology—133(4):1548-54 (1993) Abstract.
Fu, K., et al., “Cyclin D1-Negative Mantle Cell Lymphoma: A Clinocopathologic Study Based on Gene Expression Profiling,”Blood—106(13):4315-21 (2005) Abstract.
Fuchs, A.R., et al., “Oxytocin Receptors in Bovine Cervix: Distrubution and Gene Expression During the Estrous Cycle,”Biol Reprod.—54(3):700-8 (1996) Abstract.
Furuta, J., et al., “Silencing of the Thrombomodulin Gene In Human Malignant Melanoma,”Melanoma Res.—15(1):15-20 (2005) Abstract.
George, J., et al., “Pre-translational Regulation of Cytochrome P450 Genes is Responsible for Disease-Specific Changes of Individual P450 Enzymes Among Patients with Cirrhosis,”Biochem Pharmacol.
Goddard Audrey
Godowski Paul J.
Gurney Austin L.
Smith Victoria
Watanabe Colin K.
Barnes Elizabeth M.
Dreger Ginger R.
Genentech Inc.
Kaufman Claire M.
Kresnak Mark T.
LandOfFree
PR03580 polypeptides does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with PR03580 polypeptides, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and PR03580 polypeptides will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3826488