Powdery composition for nasal administration

Details Powdery composition for nasal administration Powdery composition for nasal administration

2005-04-19

2005-04-19

Wang, Shengjun (Department: 1617)

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Particulate form

C424S489000

Reexamination Certificate

active

06881423

ABSTRACT:
A powdery composition for nasal administration, where(1) the composition contains (i) a drug, (ii) a water-absorbing and gel-forming base material such as hydroxyprophyl cellulose or hydroxpropylmethyl cellulose and (iii) a water-absorbing and water-insoluble base material such as crystalline cellulose or α-cellulose,(2) wherein the amount of water-absorbing and gel-forming base material is about 5-40 wt. % based on the total of the water-absorbing and gel-forming base material and the water-absorbing and water-insoluble base material, and(3) wherein the drug is unevenly dispersed more on/in the water-absorbing and water-insoluble base material than on/in the water-absorbing and gel-forming base material.

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Hormone Metabolic Research, vol. 22, 1990, pp. 170-174, “Biological Activity of Nasally Administered Insulin in Normal Subjects”, Martha S. Nolte et al.
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International Search Report, Jun. 6, 1997.

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