Powder-layered morphine sulfate formulations

Details Powder-layered morphine sulfate formulations Powder-layered morphine sulfate formulations

1994-05-25

1995-05-02

Page, Thurman K.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Capsules

424459, 424460, 424461, 424462, 424490, 424492, 424494, 424496, 424497, 424498, A61K 948, A61K 914

Patent

active

054117453

ABSTRACT:
An oral dosage form of morphine is formulated by powder-layering an homogeneous mixture of morphine sulfate and hydrous lactose impalpable onto inert beads to obtain a multiparticulate product. A plurality of the powder-layered beads may be administered either in immediate release form or in an extended release form by coating with a hydrophobic material.

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