Surgery – Respiratory method or device – Means for mixing treating agent with respiratory gas
Patent
1992-08-14
1994-06-14
Burr, Edgar S.
Surgery
Respiratory method or device
Means for mixing treating agent with respiratory gas
12820323, A61M 1500
Patent
active
053207149
DESCRIPTION:
BRIEF SUMMARY
FIELD OF THE INVENTION
The invention relates to a powder inhaler including a reservoir for powdery drugs, a metering device and a gas passage duct.
PRIOR ART
Numerous powder inhalers are known. A problem in the known powder inhalers is the insufficient protection against air humidity and the division, which is made difficult as a result of the latter, of a powdery drug conglomerate under the effect of flow of a gas or gas mixture into small particles, whose size must be within appropriate limits so that they can pass into the sites of action intended for them in the human respiratory tract. Operation of the known powder inhalers is complicated, as a result of which use by handicapped people and use in situations of stress are not guaranteed. Additionally, an indication of the remaining quantity of the drug which can still be applied would be desirable. In known powder inhalers, there is the risk of dose fluctuations. Furthermore, in terms of their constructional size, known powder inhalers exceed pocket size and thus comply only to a limited extent with appropriate practical use.
DESCRIPTION OF THE INVENTION
One object of the invention is seen in achieving an application of powdery drugs by inhalation with the greatest possible certainty of application as the result of simple, invariable sequence of operation and precise metering by pushing the button only once. Moreover, it is to be possible for the application, that is to say the inhalation, to take place independently of the state of the button triggering the metering, that is to say it is to be possible for the button to remain pressed during the application or to be released previously.
A further aim of the invention consists in designing the exchange of the drug reservoir to be simple and inevitable and in not permitting operation errors. Additionally, the drug reservoir is to be implementable with the least amount of material and with simple contours in order to achieve cost-effect refilling with drugs, a low material weight relative to the volume to be received and a small amount of packaging. In addition to precise metering of the drug, the drug powder is to be separated to the largest possible extent during the application. Additionally, the powder applicator is to be as easy as possible to clean, for example by a jet of water.
These objects are achieved by powder inhalers including a reservoir for powdery drugs, a metering device and a gas passage duct.
It has been shown that an improved separation of powder agglomerates of active substances can be achieved by a secondary flow separating chamber. This leads to a greater proportion of the drug being deposited not in the mouth and throat area, but at the desired destination in the lung.
The subject of the invention is therefore constituted by powder inhalers, in which the gas passage duct communicates with a secondary flow separating chamber.
A further subject of the invention is constituted by powder inhalers, whose metering device consists of a metering drum, which can be rotated about a camshaft, having rams which are displaceable perpendicular to the axis of rotation through the camshaft in openings in the wall of the metering drum which is rotated further through the angle between two rams in each case when the push-button is actuated.
A further subject of the invention is constituted by powder inhalers, whose reservoir is mounted in a guide bush and is pressed by a compression spring against the metering drum in an interlocking manner.
A further subject of the invention is constituted by powder inhalers, in which a movable substrate plunger is provided in the reservoir, which substrate plunger is loaded by a substrate spring as soon as the powder inhaler is activated by a push-button.
BRIEF DESCRIPTION OF THE DRAWING
The single FIGURE of the drawing is a schematic sectional view of the powder inhaler according to the present invention.
DESCRIPTION OF THE PREFERRED EMBODIMENT
A push-button 1 is integrated in the housing 29 of the powder inhaler. Said push-button is pushed upwards
REFERENCES:
patent: 2432946 (1947-12-01), Theunissen
patent: 2540059 (1951-01-01), Stirn et al.
patent: 2622594 (1952-12-01), Brooks
patent: 3464469 (1969-09-01), Belz
patent: 3554412 (1971-01-01), Hayashi et al.
patent: 3656518 (1972-04-01), Aronson
patent: 4047525 (1977-09-01), Kulessa
patent: 4428709 (1984-01-01), Peters
patent: 4721233 (1988-01-01), Asada
patent: 5033463 (1991-07-01), Cocozza
patent: 5113855 (1992-05-01), Newhouse
patent: 5176132 (1993-01-01), Drought et al.
Burr Edgar S.
ByK Gulden Lomberg Chemische Fabrik GmbH
Raciti Eric P.
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