Powder formulations containing tiotropium suitable for...

Details Powder formulations containing tiotropium suitable for... Powder formulations containing tiotropium suitable for...

2005-04-19

2005-04-19

Henley, III, Raymond J. (Department: 1614)

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Particulate form

C514S291000

Reexamination Certificate

active

06881422

ABSTRACT:
A method of making a physically stable and homogenous powdered pharmaceutical composition comprising a tiotropium salt and a physiologically acceptable excipient, the method comprising:(a) suspending the tiotropium salt and the physiologically acceptable excipient in a suspending agent in which the tiotropium salt and the physiologically acceptable excipient are essentially insoluble to obtain a suspension; and(b) removing the suspending agent from the suspension of step (a) to obtain the pharmaceutical composition,the pharmaceutical composition itself, and method of treating respiratory diseases, especially chronic obstructive pulmonary disease and asthma, in a patient in need thereof by administering an effective amount of the pharmaceutical composition to the patient.

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