Potentiation of immunogenic response

Details Potentiation of immunogenic response Potentiation of immunogenic response

1998-11-17

2000-02-15

Stucker, Jeffrey

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Virus or component thereof

4241841, 4242041, A61K 39145, A61K 3938, A61K 3912

Patent

active

060249633

ABSTRACT:
An enhanced immune response to antigens, particularly normally weakly-immunogenic viral antigens, such as the HA antigen from influenza virus, is achieved by coadministering the antigen in two different physio-chemical forms, particularly to enable presentation of antigen both by B cells and accessory cells.

REFERENCES:
patent: 4496538 (1985-01-01), Gordon
patent: 4619828 (1986-10-01), Gordon
patent: 4950480 (1990-08-01), Barber et al.
Balkovic et al., Antiviral Research, (1987), 8:151-160.
W.E. Paul, ed. Fundamental Immunology, (1984), p. 163 and tables 5-6.
W.R. Clark, ed., Expermental Foundations of Modern Immunology, (1980), p. 37.
Singer et al., Ann. Rev. Immunol., (1983), 1:211-241.
Parker et al., The FASEB Journal, (Oct. 1991), vol. 5, pp. 2771-2784.
Eynon et al., Transplantation Proceedings, (Feb. 1991), vol. 23, No. 1, pp. 729-730.
Eynon et al., J. Exp. Med., (Jan. 1992), vol. 175, pp. 131-138.
Myers, The FASEB Journal, (Aug. 1991), vol. 5, pp. 2547-2553.
Abbas et al., J. Immun., (Sep. 1985), vol. 135, No. 3, pp. 1661-1667.
Grey et al., J. Immun., (Dec. 1982), vol. 129, No. 6, pp. 2389-2395.
Malynn et al., J. Immun., (Aug. 1985), vol. 135, No. 2, pp. 980-987.
Unanue, Ann. Rev. Immunol., (1985), vol. 2, pp. 395-428.
Wireblauer et al., Immun. Letters, (1989/1990), vol. 23, pp. 257-262.
Katz et al., Transplant. Rev., (1975), vol. 22, pp. 175-195.
Sprent, J. Exp. Med., (1978), vol. 147, pp. 1142-1158.
Sprent, J. Exp. Med., (1978), vol. 147, pp. 1159-1174.
Swierkosz et al., J. Exp. Med., (1978), vol. 147, pp. 554-570.
Singer et al., J. Exp. Med., (1981), vol. 154, pp. 501-516.
Lanzavecchia, Nature, (Apr. 1985), vol. 314, pp. 537-539.
Laver et al., Virology, (1976), vol. 69, pp. 511-522.
Butini et al., J. Cell Biochem. Suppl., (1994) Abstract J30b, 18B.
Haynes, Science, (1993), vol. 260, pp. 1279-1286.
Maizels et al., Eur. J. Immunol., (1980), vol. 10, pp. 509-515.
Becker et al., Vaccines 93, (1993), pp. 347-351.
Haynes, et al.: Update on the Issues of HIV . . . : DUODECIM: 28: pp. 39-41, 1996.
Haynes, et al.: Scientific and Social Issues of . . . : Science: vol. 260: pp. 1279-1286, May 1993.

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